Syngene, a world-leading manufacturer of image analysis solutions, is pleased to announce its Dyversity multi-application image analyser is being used by scientists in The Cancer Research UK Cambridge Research Institute (CRI) at the University of Cambridge, one of Europe’s major cancer research hubs, to accelerate the pace of research on proteins and DNA associated with a variety of different cancers.
Using Dyversity to analyse fluorescent and chemiluminescent Western blots
Researchers at The Cancer Research UK Cambridge Research Institute (CRI) are using a Dyversity system to accurately analyse fluorescent and chemiluminescent Western blots labelled with various Qdot®s and ECL respectively. They are also using the system to image agarose gels containing DNA stained with SYBR® Safe DNA gel stain. The information from the gels and blots is being used to map genes and proteins associated with cancers and is helping scientists at the CRI to provide data, which could lead to the development of new therapies for these life threatening diseases.
The Dyversity system installed at the CRI contains a high-resolution 16 bit, CCD camera with intelligent control software specifically for chemiluminescence. Additionally, their system has a computer controlled lens that moves simultaneously with the motorised sample stage. This ensures the Dyversity can quickly focus to produce high quality images with perfect contrast, without any of the time consuming trial and error imaging usually associated with capturing images of chemiluminescent blots.
“Using Dyversity saved us a great deal of time”
Dr Jane Gray, Senior Scientific Officer at the Cancer Research UK Cambridge Research Institute, said: “Since we have such a diverse range of cancer projects ongoing at the institute we need an imager that offers versatility and flexibility. We saw the Dyversity system at a proteomics meeting and were impressed by the number of different applications it could be used for. We reviewed it alongside another imager and found that the GeneSnap software and iChemi processor were really easy to use, which is why we decided this was the right system for us.”
“Since we installed Dyversity in 2009, everyone has been able to rapidly set the right exposure for their chemiluminescent Westerns and have imaged multiplex fluorescent Westerns with up to two different colours on one image, which has saved us a great deal of time. We also use the system for Safe Imaging of DNA gels and it is sensitive enough to easily detect these bands, so Dyversity has proved to be the perfect imager for our work,” added Dr Gray.
Laura Sullivan, Syngene’s Divisional Manager commented: “At Syngene we spent months developing Dyversity to be simple to use and it is an excellent endorsement when such a prestigious cancer centre is delighted with the system’s performance for so many different fluorescence and chemiluminescence applications. This clearly indicates to researchers who don’t want to spend hours of frustration trying to obtain accurate results that they should look no further than a Dyversity system.”
For further information, contact
Jayne Arthur, Syngene, Beacon House, Nuffield Road, Cambridge, CB4 1TF, UK.
Tel: +44(0) 1223-727123 Fax +44 (0) 1223-727101
Email: jayne.arthur@syngene.com Web site: www.syngene.com
Jane Gray, Ph.D., Senior Scientific Officer, The Cancer Research UK Cambridge Research Institute, Robinson Way, Cambridge CB2 0RE, UK.
Tel: +44 (0)1223 404 218 Fax: +44 (0)1223 404 208
E.mail: jane.gray@cancer.org.uk Web site: www.cancer.org.uk
About the Cambridge Research Institute
The Cancer Research UK Cambridge Research Institute is a major new research centre which aims to take the scientific strengths of Cambridge to practical application for the benefit of cancer patients. The Institute is a unique partnership between the University of Cambridge and Cancer Research UK. It is housed in the Li Ka Shing Centre, a state-of-the-art research facility located on the Cambridge Biomedical Campus which was generously funded by Hutchison Whampoa Ltd, Cambridge University, Cancer Research UK, The Atlantic Philanthropies and a range of other donors.
For more information visit www.cambridgecancer.org.uk.
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